GC-MS Analysis and In Silico Approaches of Indigofera heterantha Root Oil Chemical Constituents
نویسندگان
چکیده
The phytochemical investigation on Indigofera heterantha root oil resulted in the identification of 121 phytochemicals using GC-MS analysis. These were docked against alpha-amylase, alpha-glucosidase enzymes. docking results suggested that Hexacosyl acetate (121) possess alpha-amylase inhibitory potential with a score ?8.2944994 and interaction enzyme was ?9.73762512, followed by 9, 12, 15-Octadecatrienoic acid, 2, 3-dihydroxypropyl ester, (Z, Z, Z)-(83) ?9.59869957, showed outstanding all stages study may be shown as most auspicious resulting from studies new antidiabetic drug. Additionally, Pharmacokinetic PASS revealed their drug-likeness, expected safety upon consumption, likely pharmacological effects.
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ژورنال
عنوان ژورنال: Compounds
سال: 2021
ISSN: ['2673-6918']
DOI: https://doi.org/10.3390/compounds1030010